학    력

1999.03. – 2006.02. 국립강릉대학교 생물학과 학사

2006.03. – 2008.02. 국립강릉대학교 – 한국과학기술연구원 강릉분원 학연협동과정학과 석사

2008.03. – 2012.02. 성균관대학교 약학대학 박사

주요경력

2012.03. – 2013.04. 한국과학기술연구원 강릉분원 천연의약센터 박사후연구원

2013.05. – 2021.10. 예일대학교 화학과 및 화학생물학연구소 박사후연구원

2021.10. – 현재    국립강릉원주대학교 생물학과 조교수

관심연구분야

인체미생물의 물질대사 및 질병관련기전

미생물로부터 신규천연물대사체 및 생합성

숙주(곤충/인체) – 미생물의 생화학적상호작용

대표수상실적

남강학술상 (한국생약학회, 2012)

대표연구논문

Hyun Bong Park^#, Zheng Wei^#, Joonseok Oh, Hao Xu, Chung Sub Kim, Rurun Wang, Thomas P. Wyche, Grazia Piizzi, Richard A. Flavell, Jason M. Crawford, Sulfamethoxazole drug stress upregulates antioxidant immunomodulatory metabolites in Escherichia coli. Nat. Microbiol. 2020, 5, 1319-1329 (^#contributed equally).

Highlighted in News & Views: Alexander, M., Turnbaugh, P.J. 2020. Microbiome: Stressed-out gut bacteria are pterin up gut inflammation. Nat. Microbiol. 5: 1316-1318. 

Hyun Bong Park^#, Tyler N. Goddard^#, Joonseok Oh, Jaymin Patel, Zheng Wei, Corey E. Perez, Brandon Q. Mercado, Rurun Wang, Thomas P. Wyche, Grazia Piizzi, Richard A. Flavell, Jason M. Crawford, Bacterial autoimmune drug metabolism transforms an immunomodulator into structurally and functionally divergent antibiotics. Angew. Chem. Int. Ed. 2020, 59, 7871-7880 (^#contributed equally).

Selected as a “Hot Paper”

Hyun Bong Park, Yick Chong Lam, Jean P. Gaffney, James C. Weaver, Sara Rose Krivoshik, Randy Hamchand, Vincent Pieribone, David F. Gruber, Jason M. Crawford, Bright green biofluorescence in sharks derives from bromo-kynurenine metabolism. iScience 2019, 19, 1277-1286.

News articles in: CNN, The New York Times, National Geographic, Wikipedia (3 references), The Guardian, Forbes, ABC News, BBC News, Newsweek, Chemical & Engineering News (C&EN), Science, ScienceDaily, PBS, Cosmos Magazine, Earth, Ars Technica, Inside Science, New Scientist, Science Alert, Yahoo Finance, and many others.

Hyun Bong Park^#, Corey E Perez^#, Karl W Barber, Jesse Rinehart, Jason M Crawford, Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster. eLife 2017, 6, e25229. (^#contributed equally)

Hyun Bong Park, Parthasarathy Sampathkumar, Corey E. Perez, Joon Ha Lee, Jeannie Tran, Jeffrey B. Bonanno, Elissa A. Hallem, Steven C. Almo, and Jason M. Crawford, Stilbene epoxidation and detoxification in a Photorhabdus luminescens-nematode symbiosis. J. Biol. Chem. 2017, 292, 6680-6694.

Hyun Bong Park, Young-Joo Kim, Jae Kyun Lee, Kang Ro Lee, and Hak Cheol Kwon, Spirobacillenes A and B, Unusual spiro-cyclopentenones from Lysinibacillus fusiformis KMC003. Org. Lett. 2012, 14, 5002-5005.

Hyun Bong Park, Hak Cheol Kwon, Chang-Ho Lee, and Hyun Ok Yang, Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. J. Nat. Prod. 2009, 72, 248-252.

Highlighted in the Faculty of 1000 (F1000) Microbiology Division (by David Newman)

대표연구특허

Jason Crawford, Tyler Goddard, Hyun Bong Park, Jaymin Patel, Anti-bacterial stilbene derivatives and methods of use, WO2020215006A1 20201022.

Hyun Ok Yang, Hak Cheol Kwon, Hyun Bong Park, Ji-Hye Yoo, A coculture of Sphingomonas strain KMK-001 and Aspergillus KMC-901 to produce new anticancer and antibiotic glionitrins, WO2009066876 A2 20090528.